Using deep learning to predict disease-associated mutations

(The University of Hong Kong) A research team led by Professor Hongzhe Sun from the Department of Chemistry at HKU, implemented a robust deep learning approach to predict disease-associated mutations of the metal-binding sites in a protein. This is the first deep learning approach for the prediction of disease-associated metal-relevant site mutations in metalloproteins, providing a new platform to tackle human diseases. The research findings were recently published in a top scientific journal Na...